GAL PrimaVie® Shilajit

Shilajit (or mumio) is practically the biomass of the primeval forests, formed under the Himalayas that lifted when the Indian subcontinent collided into Eurasia. Several million years of composting under anaerobic conditions resulted in numerous unique and valuable compounds; moreover, this mass contains countless valuable trace elements as well. Thousands of years ago, people noticed that monkeys in the Himalayas regularly eat a strange, black, tar-like material, which gave them extraordinary health and longevity. Both Ayurveda and Tibetan medicine practitioners consider it among the most effective rejuvenating substances.

In modern times, its beneficial effects on mitochondria, the energy producing unit of the cells, have been scientifically recognized, along with the fact that it supports the hormonal system. Similarly to ashwagandha, shilajit is also an adaptogen and improves physical and mental performance; however, shilajit is primarily used as a rejuvenating agent and as an aphrodisiac.

The most famous and recognized researcher of shilajit is Professor Dr. Shibnath Ghosal., a published author on the subject (Shilajit in perspective). The professor recognized that there was an inherently large difference between shilajits collected from different locations, and also that a lot depended on the method of extraction. Many shilajits are standardized only for fulvic acids from the important active components, and are deficient in other active substances and trace elements. Our comprehensive testing techniques on many commercial shilajit and mumio products demonstrated that they were ineffective and our results have confirmed this

Professor Dr. Shibnath Ghosal and his team have developed a shilajit extract patented under the name PrimaVie®, which contains all active compounds in their appropriate natural ratio. Large batches can be produced, without any contaminating substances. This is due to the precisely selected clean source site and the traditional extracting method that they applied (using only clean water, without chemicals). The consistent and perfect quality is assured by using modern analyzing methods. It is important to note that the effects of PrimaVie® Shilajit have been demonstrated in human clinical trials, contrary to other similar products.Professor Dr. Shibnath Ghosal and his team have developed a shilajit extract patented under the name PrimaVie®, which contains all active compounds in their appropriate natural ratio. Large batches can be produced, without any contaminating substances. This is due to the precisely selected clean source site and the traditional extracting method that they applied (using only clean water, without chemicals). The consistent and perfect quality is assured by using modern analyzing methods. It is important to note that the effects of PrimaVie® Shilajit have been demonstrated in human clinical trials, contrary to other similar products.

Based on the above, we consider PrimaVie® Shilajit as the highest quality extract, thus we used this in our product. As Western medicine has started to pay attention to shilajit only recently, many of its effects are not yet confirmed. Effects of shilajit already confirmed in human clinical studies.

Rejuvenating the hormone system and increasing fertility both in healthy and infertile males

In a study conducted in 2009, infertile males were given daily 200mg PrimaVie® Shilajit (2×100mg) for 90 days. Their total and healthy sperm count increased significantly, so did sperm motility, while the amount of the oxidative damage marker malondialdehyde in the ejaculate decreased; furthermore, substances implying infection or inflammation (epidermis cells and pus) also decreased or disappeared. Besides, blood testosterone levels increased by 23.5%. In contrast, these values did not improve but rather got worse in the group receiving ineffective placebo. 

In order to determine whether it has any beneficial effects on the hormone system of healthy men, another study was performed in 2015. A daily dose of 500mg (2×250mg) PrimaVie® Shilajit was given for 90 days for healthy middle-age males with normal or high testosterone levels. Both their total and free testosterone levels increased significantly by 20%, while those of the placebo group decreased by 25-36%. Such a decrease in the placebo group is astonishing, it was probably due to the effect of seasons and the associated changes in the temperature and the light cycle on the level of testosterone. This either means that in this dosage PrimaVie® Shilajit can prevent the testosterone-reducing effects of external factors, or that had they performed the study in another time of the year, they would have had measured an increase exceeding 20%. Either way, in males consuming 500mg PrimaVie® Shilajit, testosterone levels increased significantly. Another interesting observation of this study is that the level of testosterone increased without the parallel increase of luteinizing hormone, from which it can be inferred that it achieves higher levels of testosterone by improving the health of testes, and not by having an effect on brain function, as other testosterone increasing substances and methods do.

In addition to testosterone, the level of another “rejuvenating” hormone, DHEA also increased significantly (+31%) in the group receiving PrimaVie® Shilajit, while it remained unchanged in the placebo group. Higher levels of DHEA increase libido, help to develop muscles, improve mental abilities and have several other beneficial effects. 

Increasing body antioxidant levels and improving blood count results
In a study in 2003, 20 out of 30 young medical students received 2g of shilajit extract (a product weaker than PrimaVie®; that is why the amount is that large) every day for 45 days, while 10 of them received placebo. Those who received shilajit increased the level of antioxidants and improved blood count results. Their levels of triglycerides and cholesterol also decreased significantly (the ratio of cholesterols improved: LDL and VLDL decreased, HDL increased). The level of vitamin C in their blood increased by 37.5%, while that of vitamin E increased by 34.7% (though shilajit contains neither vitamin C, nor vitamin E). More importantly, the amount of one of the body’s most essential “own” antioxidants (SOD) in their blood also increased by 25.6%. There was not any change in these parameters in the placebo group. 
Rejuvenating effect through enhancing collagen synthesis and inhibiting collagen breakdown

In a recent study in 2016, the long presumed positive effects of PrimaVie® Shilajit on collagen synthesis were demonstrated. Tissue samples were obtained from participants consuming 500mg PrimaVie® Shilajit daily (2×250mg) for 12 weeks. A significant upregulation of the genes of the so-called extracellular matrix was detected. The synthesis of multiple collagen protein types increased, as well as elastin synthesis, while the activity of their degrading enzymes decreased. For this study, tissue samples were obtained with biopsy from the thighs, thus these results prove its positive effects directly only on muscles and connective tissues. [4] However, from the fact that it boosts collagen synthesis and inhibits its degradation, we can expect that it has a beneficial effect on skin, bones and connective tissues as well, as these have high collagen protein content, which decreases from its healthy high levels as we age.

In February 2016, a new study was initialized to investigate the effects of 250-500mg PrimaVie® Shilajit on the skin, with the participation of 45 women. This is still an ongoing study, we have to wait for the results until 2019... [5] Other effects, investigated only in in vivo (performed on living animals) studies

Easing arthritic pain and inflammation

In 2012, researchers asked 10 dog owners to mix 500mg PrimaVie® Shilajit daily for 150 days into the food of their dogs who were suffering from osteoarthritic pain. A remarkable improvement could be observed on the dogs already after 60 days, improving further with continued administration. [6]

Others
• It promotes the absorption, utilization  and effects of coenzyme Q10.
• It improves the function of the energy production units of cells (mitochondria).
• It is effective against chronic tiredness (due to its  balancing effects on the HPA-axis).
• It acts against the development of dependence  (drugs/alcohol).
• It enhances physical perseverance and performance.
• It decreases the value of CPR, which marks  the level of inflammation in the body.
• It helps the absorption of nutrients and also  detoxification, primarily the excretion of heavy metals.

Recommended dosage 2×125mg or 2×250mg PrimaVie® Shilajit daily, that is, 2×1 or 2×2 pills. It is best to take it during meals or after them. If possible, do not take it with tap water.

Disclaimer: Pursuant to the regulations by the European Union also effective in Hungary, dietary supplements are food products, the purpose of which is to supplement conventional diet, and which contain nutrients or other substances - separately or in combination - with nutritional or physiological effect. According to the official statement, these products are not medications, have no healing effect, and are not suitable for treating or preventing diseases. GAL VitalSynergyTech Kft. respects the provisions of EszCsM Decree 37/2004 (IV. 26.) – which is a legal source for the aforementioned – as well as the requirements stipulated by the Hungarian Competition Authority. We hereby represent that our articles about the agents contained in our products have been assembled solely on the basis of the latest independent and relevant research, upon in-depth study of their interrelations, and serve the purpose of presenting them with the aim of providing information to our receptive and inquisitive Readers. These texts do not aim at boosting sales, and do not encourage for the purchase of our products. The only reason for our Customers to honor us with their recurring orders should be the fact that they have experienced the beneficial effects of GAL products. This is what we believe in, this is what we work for. 

References:
1. Clinical evaluation of spermatogenic activity of processed Shilajit in oligospermia. T. K. Biswas, S. Pandit, S. Mondal, S. K. Biswas, U. Jana, T.Ghosh, P. C. Tripathi, P. K. Debnath, R. G. Auddy & B. Auddy. Andrologia 42, 48–56 (2009).
2. Clinical evaluation of purified Shilajit on testosterone levels in healthy volunteers. S. Pandit, S. Biswas, U. Jana, R. K. De, S. C. Mukhopadhyay & T. K. Biswas. Andrologia 2015, xx, pp. 1–6 1–6
3. Pravenn Sharma et al.: EVALUTION OF ITS EFFECTS ON BLOOD CHEMISTRY OF NORMAL HUMAN SUBJECTS. Ancient Science of Life Vol : XXIII(2) October, November, December 2003
4. The Human Skeletal Muscle Transcriptome in Response to Oral Shilajit Supplementation. Amitava Das, Soma Datta, Brian Rhea, Mithun Sinha, Muruganandam Veeraragavan, Gayle Gordillo, and Sashwati Roy. Journal of Medicinal Food, Vol 19 (7), 2016, 701–709.
5. Gayle Gordillo, Associate Professor, Ohio State University. ClinicalTrials.gov identifier: NCT02762032
6. Anti‐Inflammatory and Anti‐Arthritic Efficacy and Safety of Purified Shilajit in Moderately Arthritic Dogs. Lawley S, Gupta RC, Goad JT, Canerdy TD and Kalidindi SR. Journal of Veterinary Science & Animal Husbandry, Vol. 1, Issue 3, pp. 1‐6.